We found that, for individuals 55 years and older, the benefits of distributing Vaxzevria largely outweighed the risks in a range of possible scenarios. In contrast, in young adults, the risks were similar or higher than the benefits. These conclusions were driven by the steep increase in the severity of infection with age [15] as well as the higher risk of TTS following vaccination

Upon completion of the vaccination campaign in the high-risk population, which could be accomplished within weeks to few months in most countries including Germany, the severe lock-down measures that have strongly affected social and economic life of many societies and that may go along with severe adverse health effects