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@MatthewV3:An active placebo is a pharmacologically active substance that does not have specific activity for the condition being treated. Antidepressant medications have little or no pharmacological effects on depression or anxiety, but they do elicit a substantial placebo effect.Jun 13, 2019

(The practice of burying negative results from trials is still quite common, as this recent Scientific American blog post points out.) After analyzing all the FDA studies, Kirsch concluded that